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Drug Incompatibility in Paediatrics

Potential drug-drug interactions in neonatology and paediatrics.

In infusion therapy, drug incompatibility is a well-known challenge. In paediatrics and neonatology, this is no exception. This makes it even more important to know which risk factors you should be aware of, and which measures you can take to protect your young patients from harmful drug interactions.

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Why Is Drug Incompatibility a Risk in Paediatrics?

“Exposure to major potential drug-drug interactions occurs in 41% of pediatric hospitations in childrens hospitals.”

Neininger MP, Buchholz P, Kiess W, SIekmeyer M, Bertsche A, Bertsche T. Incompatibilities on paediatric intensive care – pitfalls in durg information. Pharmazie 2018;73(10): 605-8.

How to Reduce the Risk of Drug Incompatibility in Children?

Risk Prevention in Pediatrics & Neonatology

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Germany

[1] Fahimi F, Sefidani Forough A, Taghikhani S, Saliminejad L. The rate of Physicochemical Incompatibilities, Administration Errors. Factors correlating with Nurses’ errors. Iran J Pharm Res 2015; 14(suppl); 87-93.

[2] RCN Royal College of Nursing. Standards for Infusion Therapy. 2010.

[3] Emami S, Hamishehkar H, Mahmoodpoor A, Mashayekhi S, Asgharian P. Errors of oral medication administration in a patient with enteral feeding tube. J Res Pharm Pract 2012; 1: 37-40.

[4] Vijayakumar A, Sharon EV, Teena J, Nobil S, Nazeer I. A clinical study on drug-related problems associated with intravenous drug administration. J Basic Clin Pharm 2014; 5(2): 49-53.

[5] Westbrook JI, Rob MI, Woods A, Parry D. Errors in the administration of intravenous medications in hospital and the role of correct procedures and nurse experience. BMJ Qual Saf 2011; 20(12): 1027-34.

[6] Neininger MP, Buchholz P, Kiess W, SIekmeyer M, Bertsche A, Bertsche T. Incompatibilities on paediatric intensive care – pitfalls in durg information. Pharmazie 2018;73(10): 605-8.

[7]Feinstein J, Dai D, Zhong W, Freedman J, Feudtner C. Potential drug-drug interactions in infant, child, and adolescent patients in children’s hospitals. Pediatrics 2015;135(1): e99-108.

[8] Leal KD, Leopoldino RW, Martins RR, Veríssimo LM. Potential intravenous drug incompatibilities in a pediatric unit. Einstein (Sao Paulo) 2016;14(2):185-9.

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