Factors affecting wound healing

Identification of factors affecting wound healing

Identification and elimination of factors that interfere with wound healing are fundamental steps in successful wound treatment. Chronic wounds are influenced not only by the circumstances in the wound (local factors) but also by the patient’s general condition (systemic factors). Wound treatment should therefore always involve an integrated approach. The important causes leading to poor healing conditions are listed below.

Local factors Systemic factors
Bacterial colonisation Cardiovascular disease
Fibrin coating and necrosis Neuropathy (diabetics) 
Wound infection Metabolic disease 
Poor wound hygiene  Malnutrition 
Poor blood supply  Medications (e.g. steroid) 
Low oxygen saturation  Immuno suppression 
Debris  Advanced age 
Pressure  Smoking